Anti-Alcohol Antioxidants Vitamin / Supplement, Pills - Ingredients

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Hair, Nails, Dehydration, and Alcohol
by Dusty R. Green, M.Ed., Research Scientist/Author

Anti-Alcohol Antioxidants have several benefits.  In one interesting study, researchers reported that a group of rats were given a dose of acetaldehyde (a poison formed as a by-product of alcohol and tobacco smoke ... stuff that causes hangovers) large enough to kill 90 percent of them.8  A different group was given a combination of vitamin C, cysteine, and vitamin B1 and there were no deaths.  As a result of this landmark study, we now know how the right combinations of vitamin B1, vitamin C, cysteine, and glutathione inhibit the free radical pathologies of acetaldehyde poisoning.

Since alcohol is extremely dehydrating and acidic, I suggest you drink a glass of water (preferably baking soda water)  with each cocktail.  Dehydration combined with acid significantly adds to headache hangovers.

In addition, consuming alcoholic beverages results in the generation of free radicals.  People who drink a lot of alcohol often suffer a hangover because of massive free radical-induced cellular damage.  This assault can wreak short-term havoc throughout the body and these same damaging free radicals are associated with accelerated aging.

An interesting side-effect of taking this supplement on a regular basis is the production of stronger/thicker nails and hair.  If you happen to be taking this supplement for hair and nails, I recommend one to three capsules three times per day.  Cysteine, is the most abundant nutrient in human hair, comprising about eight percent.10  Deficiency can lead to unhealthy hair and/or hair loss and dandruff.

Supplement Facts:  Serving Size - 6 caps.  Servings / Container - 16.  100 Caps/Bottle

Amount / Serving

Vitamin C (as ascorbic acid) (Roche)

3000 mg

Vitamin E (as D-alpha tocopheryl)

50 IU

Thiamin (vitamin B1)(as thiamine HCl)

1000 mg

Selenium (as selenium selenate)

25 mcg

N-acetyl-L-cysteine

600 mg

Glutathione (reduced)

50 mg

Benfotiamine

50 mg

HepatoProtection Complex

 

Chlorophyllin (from sodium copper chlorophyllin)

20 mg

Leucoselect Grapeseed extract(Vitis vinifera) [standardized to 95% proanthocyanidins (19 mg)]

20 mg

Silymarin [from Milk Thistle (Silybum marianum) seed extract]

20 mg

Picroliv Picrorhiza kurroa root extract [standardized to 4% kutkin] (0.6 mg)

15 mg

Barley grass juice 24:1 extract powder

15 mg

Resveratrol [from whole red grape (Vitis vinifera) and Polygonum cuspidatum root extract]

5 mg

Other Ingredients:  Gelatin, magnesium stearate, rice flour.  This product contains NO wheat, yeast, gluten, corn, dairy.  Contains NO sugar, artificial color, sweetener, flavors or preservatives.

Leucoselect is a registered trademark of Indena USA. U.S. Reg No. 2294439.
Picroliv is a registered trademark of Sabinsa Corp.


Astronomical Cost of Hangovers
Reprinted by permission from Bill Faloon of The Life Extension Foundation

A landmark study published in the Annals of Internal Medicine detailed the enormous economic costs of lost productivity attributable to hangovers: "In the United States, related absenteeism and poor job performance cost $148 billion annually (average annual cost per working adult, $2,000)."1

Protecting against alcohol toxicity
A study published in the journal Alcohol demonstrated how antioxidants help to maintain a healthy brain.2  Another study in the journal Artery confirmed a specific toxic metabolite of alcohol (acetaldehyde) and identified an antidote (N-acetyl-cysteine):  "All known pathways of ethanol metabolism result in the production of acetaldehyde, a highly reactive compound.  N-acetyl-cysteine, an analogue of the dietary amino acid cysteine, binds acetaldehyde, thus preventing its damaging effect on physiological proteins."3

These findings are not surprising, considering that the consumption of alcohol inflicts massive free radical damage throughout the body.  When people are exposed to a known toxic substance such as alcohol, it makes perfect sense to take a proven antidote-namely, antioxidants.

Life Extension's Anti-Alcohol Antioxidants with HepatoProtection Complex is an improved formula containing additional antioxidants designed to suppress free radicals, neutralize toxic alcohol metabolites such as acetaldehyde,4-7 and protect against liver toxicity and hepatic injury commonly associated with alcohol consumption.  In addition to vitamin B1, vitamin C, N-acetyl-cysteine and benfotiamine, this new formula's HepatoProtection Complex provides potent doses of these novel antioxidants:

  • Chlorophyllin, an antimutagenic agent that protects the body from oxidative stress than can stimulate cellular mutation.
  • Leucoselect grapeseed extract, silymarin (from milk thistle), and resveratrol, three hepatoprotective agents that aid in reducing mutagenic compounds from potentially toxic xenobiotics and protecting cells from free radial-induced oxidative stress.
  • Picroliv Picrorhiza kurroa root extract, containing antioxidant kutkins that scavenge alcohol-induced excess free radicals, guard against alcohol-induced damage to cells by lipid peroxidation, and stimulate regeneration of cells (hepatocytes).
  • Barley grass juice 24:1 extract, which enhances the enzyme aldehyde dehydrogenase, thus inhibiting the formation of acetaldehyde malondialdehyde.

Taking the proper supplements before and after drinking can help mitigate hangover effects experienced by people suffering from acute alcohol toxicity.


Dosage and Use:

  • Take one capsule with each alcoholic beverage,
  • A maximum of six capsules per day,
  • If no capsules are taken with alcoholic beverages, take six capsules at bedtime.

Caution:  This product does not prevent, reduce or modify any of the mental impairment effects that alcohol induces.  Consuming alcohol and taking this product will not allow a person to safely operate a vehicle or any other equipment.  Do not drink and attempt to drive.

Editors Note:  For those with addictions, an additional consideration is to use kudzu and d,l phenylalanine in association with l-glutamine for lessening the desire for alcohol and carbohydrates.  Lithium orotate also shows promise in the addictions arena along with n-acetyl l-cysteine (NAC) for gambling addictions and/or other addictive behavior support.  There seems to be a synergistic relationship with all of these combined compared to any one single nutrient alone.  In addition, activated charcoal/bentonite clay is the preferred choice for detoxification of toxic substances and other poisons that can build-up in our bodies.

Warnings

  • Keep out of reach of children,

  • Do not exceed recommended dose,

  • If you have a bad reaction, discontinue use immediately,

  • When using Anti-Alcohol Antioxidants w/HepatoProtection Complex, please inform your physician.

Anti-Alcohol Antioxidants Vitamins - Side Effects, Treatment, Facts | Diabetes & Alcohol |
Fatty Livers, Alcohol, & Artichoke | HepatoPro | Liver Efficiency Formula

References:
1. Wiese JG, Shipak MG, Browner WS. The alcohol hangover. Ann Intern Med. 2000 Jun 6132(11):897-902.
2. Altura BM, Altura BT. Association of alcohol in brain injury, headaches and stroke with brain-tissue and serum levels of ionized magnesium: a review of recent findings and mechanisms of action. Alcohol. 1999 Oct;19(2):199-30.
3. Vasev S, Mian T, Longerich L, et al. N-acetyl-cysteine attenuates ethanol induced hypertension in rats. Artery. 1995; 21(6):312-6.
4. Wickramasinghe SN, Hasan R. In vivo effects of vitamin C on the cytotoxicity of post-ethanol serum. Biochem Pharmacol. 1994 Aug 3;48(3):621-4.
5. Mitchell JJ, Paiva M, Heaton MB. The antioxidants vitamin E and beta-carotene protect against ethanol-induced neurotoxicity in embryonic rat hippocampal cultures. Alcohol. 1999 Feb; 17(2):163-8.
6. Shman'ko, W. The selenium content of the body in experimental animals and its effect on the functional biochemical status of the liver in toxic injury. Fiziol Zh. 1996; 42(12):65-72.
7. Agar E, Boznak M, Amanvermez R, et al. The effect of ethanol on lipid peroxidation and gluathione level in the brain stem of rats. Neuroreport. 1999 Jan 3;10(8):1799-801.
8.Oeriu, S., and Vochitu, E. "The effect of the administration of compounds which contain sulfhydril groups on the survival rates of mice, rats, and guinea pigs." Journal of Gerontology. 1965, 20:417.
9. Anderson, R., Theron, A.J., and Ras, G.J. "Regulation by the antioxidants ascorbate, cysteine, and dapsone of the increased extracellular and intracellular generation of reactive oxidants by activated phagocytes from cigarette smokers." American Review of Respiratory Diseases. 1987, 135:1027.
10. Pearson, D. and Shaw, S. Life Extension. Warner Books, New York. 1982, p. 267.
11. Pearson, D. and Shaw, S. "Cysteine-the sulfur connection." Anti-Aging News. 1982, 2:5.
12. Forman, H.J., Rotman, E.I., and Fisher, A.B. "Role of selenium and sulfur containing amino acids in protection against oxygen toxicity." Laboratory Investigation. 1983, 49:148.
13. Springe, et al. "Protectants against acetaldehyde toxicity: Sulfhydryl compounds and ascorbic acid." Federal Proceedings. Federation of the American Society for Experimental Biology. 1974, 172:233.
14. Sprince, et al. "L-ascorbic acid in alcoholism and smoking: Protection against acetaldehyde toxicity as an experimental model." International Journal for Vitamin and Nutrition Research. 1977, 47:185.

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