Chromate Chromium GTF Picolinate Polynicotinate Benefits, Side Effects - Dose

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Chromate Chromium GTF
Picolinate Polynicotinate Benefits, Side Effects - Ingredients/Dose

Chromate Chromium GTF Polynicotinate (yeast free)
200 mcg, 240 tablets

Chromium polynicotinate is an essential trace mineral, niacin-bound, and an absorbable form that may be used as part of your diet side effects free.

Safety issues concerning the use of the picolinate form of chromium have been in question for the past few years.  Aside from genetic damage, picolinate is known to "break-off" from its chromium-bond and cause adverse side effects.  Chromium picolinate is a patented version of the trace mineral chromium.  Picolinic acid is produced in the human body, apparently for the purpose of improving the cellular uptake of trace metal ions.  Scientists have demonstrated that several minerals in picolinate form are better assimilated than most other forms of the same minerals.

Chromium polynicotinate is a well assimilated form which may have more benefits for certain conditions than does the picolinate form. 

Chromium polynicotinate seems to have some definite advantages over chromium picolinate, including even better bioavailability.  It now appears that niacin-bound chromium is a safer form of chromium for supplementation.  Some studies have also shown that niacin is necessary for chromium supplements to be of benefit.

Chromium aspartate, an unpatented and much less expensive form of chromium, appears also be well absorbed but it does not have the benefit of the level of scientific testing that the patented forms have.

Chromium occurs in two chemical forms, called trivalent and hexavalent.  The hexavalent form is usually a byproduct of the metallurgy industry (for example, chrome automobile parts).  It may have toxic side effects if inhaled.  Although it is not recommended for ingestion, when the hexavalent form is consumed orally it is quickly converted into the harmless, bioavailable trivalent form.  Chromium intended for dietary supplementation is always trivalent.

In contrast to hexavalent chromium, trivalent chromium is an essential micronutrient that is exceptionally well tolerated.  Although still somewhat controversial, chromium supplementation is believed by many reputable scientists and physicians to be an important tool in health virtually  side effects free.

A review of the scientific literature indicates the reason many people do not respond to chromium is that the dose they take is too small.  For many years, Source Naturals has included niacin in its chromium supplements.  In the body, chromium combines with niacin.  Chromium Polynicotinate is a niacin-bound, absorbable form that may be used as part of your diet.  For instance, supplementing with 200-400 mcg per day of chromium has not produced consistent benefits, whereas doses of 600-1000 mcg per day have.

Supplement Facts:  Serving Size - 1 Tablet.  Servings/Container - 240

Amount / Serving

Niacin (vitamin B3) (flush free from inositol hexanicotinate)

690 mcg

Chromium GTF (as chromium polynicotinate - ChromeMate) trivalent

200 mcg

Other ingredients:  Rice flour, gelatin, and water.  This product is yeast-free.

ChromeMate is a trademark of InterHealth, N.I.

Dosage and Use:  Take two to three capsules daily.  This product is most effectively utilized when taken with meals.


  • Keep Chromium GTF Polynicotinate out of reach of children,
  • Do not exceed recommended dose,
  • If you have a bad reaction or side effects, discontinue use immediately,
  • When using Chromium GTF Picolinate Polynicotinate trivalent, please inform your physician,
  • Supplement to be taken in conjunction with a healthy diet and regular exercise program.  Results may vary.

Ultra Chromium Polynicotinate - Ingredients/Dose

Pricing Information:  Chromate Chromium GTF Polynicotinate


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