Collagen Type II Shown to Support Skin Health and Joint Strength - Page 2
Reprinted by permission from Pat
Whittington of Vitamin Research
||Hydrolyzed vs. Native Collagen
At the summer 2003 meeting of the British Nutrition Society, Oesser and Seifert
announced the results of their experiments on the effects of the type II
collagen on chondrocytes. They studied the effects of hydrolyzed vs. native
(undigested) type II collagen on the activity of mature bovine chondrocyte
cells. They found that native collagen had no stimulatory effect on chondrocytes,
but cells fed the hydrolyzed collagen increased their production of type II
collagen 250 percent.8
At the meeting, Dr. Oesser remarked: This is the first time a cell culture
model has shown that collagen hydrolysate, can lead to an increase in cartilage formation.
It is very
plausible that collagen hydrolysate, when taken as a supplement to our normal
diet, may help activate the synthesis of collagen in cartilage. Particularly in
situations in which cartilage is under massive stress [e.g., arthritis, obesity,
sports injury, etc.], the intake of collagen hydrolysate could be highly
significant and reduce degenerative changes.
Collagen Type II vs. Skin Aging
Dr. Nelson Novick is a practicing M.D., and associate clinical professor of
dermatology at The Mount Sinai School of Medicine, as well as a dermatology
clinic chief at The Mount Sinai Medical Center. In a recent
article on Tips for at-home anti-aging skin care, he commented on
the usefulness of type II collagen for promoting youthful skin.
I recommend daily oral supplementation with Biocell Collagen [Type] II, a unique combination of collagen II,
hyaluronic acid and
chondroitin sulfate (HA's companion that builds cartilage)
to nourish the skin from the inside out where topical applications cannot
reach, he said. This dietary supplement provides the only natural and
bioavailable source of these three elements needed to maintain skin moisture and
elasticity. This complex concentrated matrix of elements, formerly only
available to plastic surgeons as injectable drugs, not only halts the appearance
of skin aging, but also potentially supports the aging process altogether ...
This supplement is not a short-term solution, such as the use of injectable
collagen; rather it is a necessary part of any regimen intended for life-long
skin tissue health.9
In a review on the role of collagen hydrolysate in bone and joint issues,
Professor Roland Moskowitz, M.D., commented on the excellent safety profile of
collagen hydrolysates.10 He noted that partially hydrolyzed collagen has been
used as a food since at least early medieval times. Various collagen hydrolysate
products have been affirmed as GRAS (generally regarded as safe) by the FDA.
also notes that Collagen hydrolysate is of interest as a therapeutic agent of
potential utility in the treatment of joint and
bone related conditions. Its high
level of safety makes it attractive as an agent for long-term use in these
Collagen Type II Dosage
Collagen Type II comes in 500 mg capsules. The standard dose is two capsules two
or three times daily. The product can be taken with or without food as desired.
Very large persons, or those with severe joint problems, may need to take larger
doses (i.e., six to eight capsules daily) while smaller persons, or those just
taking collagen as a skin/joint maintenance supplement, may only need two to
four caps daily.
Regular use of Collagen Type II may also improve
wound healing,2,3 as well as
improve quality and growth of hair and nails.9,10 Side effects with collagen hydrolysates are rare, but may include a sensation of unpleasant taste, a
feeling of heaviness in the stomach, a bloated feeling or burping.10
1. Sardi, B. Restoring youth with hyaluronic acid. Total Health for Longevity,
2. Anderson, I. The properties of hyaluronan and its role in wound healing. Prof
Nurse, 2001, 17:232-35.
3. Greco, R. et al. Hyaluronic acid stimulates human fibroblast proliferation
within a collagen matrix. J Cell Physiol, 1998, 177:465-73.
4. Ghersetich, I. & Lotti, T. Hyaluronic acid in cutaneous intrinsic aging. Int
J Dermatol, 1994, 33:119-22.
5. Champe, P. & Harvey, R. Lippincotts Illustrated Reviews: Biochemistry.
Philadelphia: J.B. Lippincott, 1994:147-55.
6. Ronca, F. et al. Anti-inflammatory activity of chondroitin sulfate.
Osteoarth & Cartilage, 1998, 6 (Suppl A):14-21.
7. Duarte, A. The Collagen Type II. 1997:39.
8. Oesser, S. & Seifert, J. Stimulation of type II collagen biosynthesis and
secretion in bovine chondrocytes cultured with degraded collagen. Cell Tissue
Res, 2003, 311:393-99.
9. Novick, N. Tips for at-home skin care. Total Health for Longevity,
10. Moskowitz, R. Role of collagen hydrolysate in bone and joints. Semin
Arth Rheum, 2000, 30:87-99.
Collagen Type 2
/ BioCell II |
Serum and Tabs |
Serum, Tabs, and DMAE Cream |
collagen Type 2) |
Cream, Rejuvenex, Na (sodium) PCA Facial Cream |
Virgin Coconut Oil