Super Bio-Curcumin - Root, Extract, Health, Benefits - Dose

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Super Bio-Curcumin by Life Extension Foundation
60 Vegetarian Capsules / 400 mg each

Curcumin was first used by Indians over 3000 years ago in traditional Ayurvedic medicine.  Modern science has found that this extract from the common spice turmeric has remarkable qualities as an antioxidant.  Over time, as our cells continue to be affected by free radicals, or oxidants, organs begin to degenerate and aging accelerates.

The body does have built-in defense mechanisms to protect itself from free radical damage, but eventually, aging and disease deplete the body's ability to keep oxidants at bay.

Curcumin can help maintain normal healthy platelet function and the normal process of bile excretion.  There are anecdotes stating that it may help with gynecomastia or gyno -- a condition associated with breast enlargement in men

Ex-Vioxx and ex-Celebrex users are turning to circumin as an alternative.

The 100% natural curcuminoids complex in Super Bio-Curcumin is a patent-pending synergistic blend of curcuminoids and sesquiterpenoids with enhanced bioavailability and sustained retention time in the body confirmed by human clinical studies.
Super Bio-Curcumin is a next generation in delivery of curcumin compounds that no longer requires high doses of curcumin to reach sustainable levels in blood plasma.  Modern science has found that curcumin has remarkable antioxidative, immunomodulatory, proapoptotic, and antiangiogenic properties.54-57  Curcumin is also found to increase detoxifying enzymes and promote healthy DNA function.58

New studies have tied inflammation to overexpression of a protein molecule called nuclear factor-kappa B (NF-kappaB).  NF-kappaB acts like a switch to turn on genes that produce the bodys inflammatory responses.  Because NF-kappaBs expression increases in aging adults, scientists have sought ways to modulate NF-kappaB and its effects in the body.

Poorly Absorbed
The problem is that curcumin is poorly absorbed into the bloodstream.  Super Bio-Curcumin absorbs up to 7 times better than conventional curcumin.  So this patented formula represents the most cost-effective way to supplement with this critical nutrient.  Studies show that one 400 mg capsule a day of this turmeric compound can provide curcumin blood levels equal to ingesting 2,500 - 2,800 mg of commercial curcumin supplements.  And, not only does this turmeric formulation provide far greater peak blood levels, but the curcumin remains in the bloodstream almost twice as long as conventional supplements.  This enhanced absorption delivery complex provides other beneficial turmeric compounds in addition to standardized curcumin.  Each 400 mg capsule of Super Bio-Curcumin is equivalent to approximately 2,772 mg of a typical 95% curcumin extract.

Supplement Facts:  Serving Size - 1 capsule.  Servings Per Container - 60.  Amount Per Serving

BCM-95 Bio-Curcumin (Curcuma longa) 25:1 extract (root) [std. to 95% Total Curcuminoids Complex with Essential Oils of Turmeric Rhizome by HPLC (380 mg)]

400 mg

Other ingredients:  Rice flour, vegetable cellulose (capsule), vegetable stearate, silica. Contains rice.  This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Bio-Curcumin and BCM-95 are registered trademarks of Dolcas-Biotech, LLC. U.S. Patent Nos. 7,883,728, 7,736,679 and 7,879,373.

Curcumin has been shown to exert powerful inhibitory effects on NF-kappaB activation within the body.59  Curcumin inhibits overexpression of NF-kappaB.  In addition, curcumin inhibits the metabolism of arachidonic acid, as well as activities of cyclooxygenase, lipoxygenase, and cytokines (interleukins and tumor necrosis factor).60

Other clinical trials suggest roles for curcumin in helping maintain healthy lipid profile, bowel, and joint functions.61,62  Curcumin can also help maintain normal healthy platelet function,63-66 and have immunomodulatory effects by inhibiting histamine release from mast cells.67

Curcumin may effectively rescue pancreatic islets from damage, the cause of deficient insulin production, without affecting the normal function of these cellular structures.68  Curcumin's multifaceted effects include protecting against estrogen-mimicking chemicals, protecting against damaging free radicals, and promoting normal cell cycle growth.

The turmeric extract in Super Curcumin has been standardized to 95% curcuminoids in order to ensure optimal quality, potency, and bioavailability.

Dosage and Use:
  Take one capsule once or twice daily with meals, or as recommended by your healthcare practitioner.  Turmeric Extract (circumin) supports the liver and healthy cholesterol levels.

Caution:  Do not take if you have gallbladder problems or gallstones.  If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.  If you are taking any medication, use only under physician supervision.  Do not take if you have a biliary tract obstruction, or during pregnancy or lactation.  High doses of curcumin on an empty stomach may cause stomach ulcers.  Do not take with anticanc drugs.

Warnings Information:

  • Keep out of reach of children,

  • Do not exceed recommended dose,

  • If you have a bad reaction, discontinue use immediately,

  • When using Super Bio-Curcumin supplements, please inform your physician.

More Information | Curcumin & Canc Support

Pricing Information: Super Bio-Curcumin w/Bioperine Supplements | Herbal Formula

References for this article:
54. Anticanc Res. 2004 Mar-Apr;24(2B):563-9.
55. Toxicol Lett. 2000 Mar 15;112-113:499-505.
56. J Pharm Pharmacol. 1997 Jan;49(1):105-7.
57. Antioxid Redox Signal. 2008 Mar;10(3):511-45.
58. Asia Pac J Clin Nutr. 2008;17 Suppl 1:265-8.
59. J Alzheimers Dis. 2004 Aug;6(4):367-7.
60. Chin Med. 2008 Sep 17;3:11.
61. Dig Dis Sci. 2005 Nov;50(11):2191-3.
62. Biochem Pharmacol. 2008 Feb 15;75(4):787-809.
63. J Endotoxin Res. 2007;13(1):15-23.
64. Prostaglandins Leukot Essent Fatty Acids. 1995 Apr;52(4):223-7.
65. Mol canc Ther. 2006 May;5(5):1371-82.
66. J Ethnopharmacol. 1993 Mar;38(2-3):113-9.
67. Mol Nutr Food Res. 2008 Sep;52(9):1031-9.
68. Eur J Pharmacol. 2007 Dec 22;577(1-3):183-91.


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