What Is DHEA's Side Effects for Women's Sexuality, Skin Aging and Health? - Page 5

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What Is DHEA's Side Effects for Women's Sexuality, Skin Aging and Health? - Page 5
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What Is DHEA's Side Effects for Women's Sexuality, Skin Aging and Skin Health? - Page 5

New Research Substantiates the Anti-Aging Properties of DHEA
By Kirk Stokel

Enhanced Well-Being and Libido Even in Challenged Populations
Studies as early as 2000 demonstrated how DHEA improved well-being and could help to manage menopause without deleterious side effects.28,66  In 2006 it was revealed that 50 mg per day of DHEA could improve psychological well-being even in challenging populations such as those with decreased pituitary function.67

DHEA exerted remarkably positive side effects on health-related quality of life in women taking long-term steroids for lupus (chronic steroid therapy can produce powerful depression and reduction in quality of life measures).68  Of particular importance, the DHEA-supplemented groups also reported improvement in sex drive and sexuality.

Additional research supports an excitatory effect for DHEA on sexuality, especially in women.

In one study, sixteen sexually functional post-menopausal women were randomly given either placebo or a single DHEA supplement of 300 mg, 60 minutes before presentation of an erotic video.69  Women in the supplement group showed significantly greater mental and physical sexual arousal during the video than did the control women. The supplemented women also reported a greater increase in positive affect (generally feeling good) compared to placebo recipients.

A 2009 animal study may shed light on some of the physical causes behind these benefits:  DHEA applied to the smooth muscle of rabbit clitoris resulted in significant relaxation,70 allowing increased blood flow and engorgement that results in enhanced sensitivity during sexual arousal.

Favorable Gene Expression for Youthful, Glowing Skin
A growing body of scientific evidence suggests that DHEA has special favorable side effects on skin health and appearance.

DHEA 25 mg

In a 2000 laboratory study, DHEA was shown to increase production of collagen, the protein that gives youthful skin its suppleness while decreasing production of the collagenase enzymes that destroy it.71  It wasn't until 2008, however, that Canadian scientists discovered more than 50 DHEA-responsive genes in the skin of women using a topical DHEA cream.72  DHEA switched on multiple collagen-producing genes and reduced expression of genes associated with production and cornification (hardening) of the tough keratinocytes that form calluses and rough skin.  The researchers concluded, DHEA could exert an anti-aging effect in the skin through stimulation of collagen biosynthesis, improved structural organization of the dermis while modulating keratinocyte metabolism.

Other unexpected benefits of topical DHEA on aging skin are emerging.  DHEA treatment increases production of sebum, or skin oil.73  Sebum not only contributes to smooth, supple skin, it also contains myriad antimicrobial components that prevent infection and irritation.  Topical DHEA also improves skin brightness and counteracts the papery appearance of aging skin, combating the epidermal thinning that is a visible hallmark of aging.73  The study, authors note, that these are beneficial side effects on skin characteristics that are rarely provided by most other topical treatments.

In the past few years alone, significant scientific substantiation of DHEA's anti-aging effects has emerged.  Its neuroprotective effects are now recognized as being vital in protecting memory and reducing depressive symptoms in older adults.  DHEA enhances bone health by improving mineralization to reduce fracture risk.  DHEA modulates immunity in a coordinated fashion by boosting resistance to infection while quelling dangerous inflammation.  DHEA supports cardiovascular health and activates genes that prevent cardiovascular risk factors, including diabetes and obesity.  DHEA is intimately involved in improving quality of life and bolstering sexual arousal, while dramatically improving the appearance of healthy, youthful skin.  As little as 50 mg of DHEA per day may favorably alter gene expression to inhibit multiple factors implicated in metabolic syndrome; boost bone strength; enhance cognitive function and memory; and ward off osteoarthritis.  DHEA topical creams allow ready application of DHEA to the site of action.

Note: Individuals who have been diagnosed with a hormone-dependent canc should not supplement with DHEA until their canc and its side effects are cured.

Warnings Information:

  • Only for adults ... keep out of reach of children,
  • Do not exceed recommended dose for maximum benefits,
  • If you have a bad reaction or side effects, discontinue immediately,
  • When using DHEA supplements for women's sex drive or sexuality, skin aging or skin health, please inform your physician.

Pricing Information: DHEA Supplements

What Is DHEA? Pg 1 | Pg 2 | Pg 3 | Pg 4 | References | DHEA and Stress | DHEA 7 Keto Info


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