Diabetes, Obesity Seen as Accelerated Aging

Diabetes, Obesity Seen as Accelerated Aging

Home Products
A-K
Products
L-Z
Amazon Shopping Terms and Conditions MX GuardDog Spam Blocker View Cart
Live Search
Buy anything from eBay!

Diabetes, Obesity Seen as Accelerated Aging

The July issue of the journal Nature Reviews Drug Discovery published a review by Rory Curtis, Bard J Geesaman and Peter DiSefano of Elixir Pharmaceuticals that documents the links between the aging process and metabolic disease.  The authors suggest that as an alternative to targeting individual diseases that occur with aging, aging itself can be targeted to treat its associated conditions.

The authors show that the regulation of aging and energy homeostasis share molecular pathways.  Many of the genes recently discovered that can be manipulated to slow the aging process belong to pathways involved in the control of metabolism.  Energy homeostasis dysregulation occurs during the aging process, when aged men and women experience a reduced ratio of lean to fat mass, and a redistribution of fat from subcutaneous to visceral areas that surround the internal organs located in the bodys trunk.  This leads to decreased insulin sensitivity and increased serum insulin, which can result in the metabolic syndrome and type 2 diabetes.  Among younger individuals who have increased visceral fat mass there is a greater risk of the development of diabetes, heart disease, hypertension, gall bladder disease, neurodegenerative disease, and a number of cancers, all of which are associated with aging.

Degree of obesity has been found to be inversely correlated with life expectancy.  Calorie restriction, which has been the most successful means so far to extend the lifespan of numerous species, prevents obesity and has been demonstrated to postpone many signs of aging and protect against a number of age-related diseases.  This life extending therapy also has been shown to affect genes involved in energy metabolism.  Calorie restriction, as well as genetically manipulating the insulin receptor in fat cells, prevents visceral obesity and its consequent insulin resistance and elevated insulin levels, in addition to extending lifespan.

The authors believe that this knowledge will aid in the development of drugs that could not only treat diabetes, obesity and other metabolic conditions, but slow the aging process itself and extend lifespan.  Professor of Molecular Biology John Kopchick, PhD, of the Department of Biomedical Sciences, Konneker Research Center, Ohio University, commented, "The article by DiStefano et al. will stimulate a paradigm shift in our thinking about aging and age-related disorders.  As pointed out by the authors, we are beginning to recognize that metabolic syndrome, in addition to being a precursor of serious diseases such as type 2 diabetes and cardiovascular disease, may be a sign of premature aging.  For patients, this translates into the potential of a variety of novel drugs emerging from the science of aging, which then will be tested clinically in the treatment of metabolic diseases.  What an exciting possibility!"

Natural/Alternative/Preventive measures to consider:  Diabetes Mellitus - Page 1 | Page 2 | Page 3 | Page 4

More Information:  Diabetes Mellitus Type 2, Exercise, Blood Sugar | Dietary Troubles - Obesity, Diabetes, Heart Disease |
Diabetes & Vitamin D |
Diabetic Retinopathy Occurs in Pre-Diabetes | Diabetic Adult Lifestyles - Late Onset Diabetes |
Early Detection - Insulin Resistance

 

Enjoy the benefits of our flat rate shipping and handling!  You receive the same great service for the same shipping price whether you order one item or one hundred!

$5.97 - Within USA only - US Post Office  5-9 business days.

$29.77 - To Canada only (see warning information here) 5-9 business days to customs check point (the only way we ship - US Post Office).

$39.77 - Outside USA only
(see warning here) 7-10 business days to your country's customs check point (the only way we ship - US Post Office).

Save 8.25% on all purchases - Texans and everyone!

It's all tax free!  You will be able to review all charges before they are charged to you.

At checkout (after you click the Add button on any of the order pages), the billing address you enter must match the address where you receive your credit card (security effects).  The shipping address you enter does not have to match.

All orders placed by Noon Central Standard Time (CST) are shipped the same day.  PO Boxes Okay.

Payment by credit card is immediate.  Payment by check adds a few more business days -- as soon as funds clear.

We do not sell the information you give us to anyone.


Protecting Your Personal Information
:
We pledge a safe and worry-free shopping experience using the industry standard for Internet security, 128-bit Secure Sockets Layer (SSL) encryption (see an online payments diagram).  SSL scrambles your personal and credit card information as it travels the Internet during the checkout process.  We utilize the Authorize.Net payment gateway.  Your credit card information is encrypted and sent to an Authorize.Net transaction server.  This server sends the data through the network to the card's bank, using a secure, proprietary connection.  When complete, you will receive an approval or decline response.  At no point is your credit card information stored on our server.

For additional information regarding the privacy of your sensitive cardholder data, please read the Authorize.Net Privacy Policy.

SmartBodyz Nutrition Home Page
1000 West 10th, Suite 218
Fort Worth, Texas 76102
Local Telephone: 817-335-1982
Email: DG[at]SmartBodyz.com - replace [at] with @
(helps prevent spam)
Copyright 1996-2017, SmartBodyz Nutrition -- all rights reserved.

Credit Card Processing

Credit Card Processing

You can shop here with safety and confidence.  We have partnered with Authorize.Net, a leading payment gateway since 1996, to offer safe and secure credit card transactions.

The information and statements made throughout this web site have not been endorsed/evaluated by the Food and Drug Administration or any other governmental authority, unless otherwise specifically noted.  We do not offer products or services for the benefits or purpose of diagnosis, prescription for, treatment of, or claims to prevent, mitigate or cure any viral or disease condition or be free from side effects.  Please, seek the advice of a competent medical professional about anything you read on our site.

BlogBlogLinks | Testimonials | Privacy | RSS Feed