NutriJoint / Glucosamine, Chondroitin Sulfate, MSM, SAM-e, Side Effects

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Glucosamine / Chondroitin / MSM / SAM-e / Omega 3 Fatty Acids / Side Effects
by Dusty R. Green, M.Ed., Research Scientist/Author

Actors James Coburn & Robert Vaughn
James Coburn, veteran actor was interviewed in The Journal of Longevity, vol. 5, #2 (1999).  Coburn talks about treatment by his conventional doctor concerning joint pain.  On the subject of steroid anti-inflamatories, he states "They didn't do anything.  They just numbed things.  It didn't help.  I went to see him [his doctor] and that was it."  He went on to say "I couldn't stand up.  It caused me such agony and pain that I never wanted to get up.  I'd break out in a sweat every time I stood up."

After trying every form of prescription drug on the market including electromagnetic therapy for his debilitating condition, his wife of 5 years turned him on to MSM.  After using it Coburn raved about MSM for helping with his long bout with joint pain side effects free.  He has become a great fan of MSM and gives it to his friends.

Actor Robert Vaughn was in town shooting a film and called Coburn for help.  He had been experiencing joint pain and couldn't raise his hands over his head.  "I couldn't even comb my hair," says Vaughn.

Coburn gave him some MSM and Vaughn came back a week and a half later excitedly demonstrating his ability to comb his hair and wave his arms above his head.  Coburn also states, "My hair grows like crazy, now.  And, my fingernails grow really quickly."

Now that Coburn is pain free he is acting again.  He says, "MSM contributed to the way I feel today.  I feel really good.  I worked 18 hours yesterday on the set and I was in every shot.  In every shot, not just every scene!  I sat down for lunch; that was it."

As with some natural remedies, the therapeutic effects of this product may not come immediately.  It may take 2 weeks to experience pain relief.  Some people do not get relief until 8 weeks after their initial dose.  In general, joints take longer than other body parts.  Regardless, when you experience pain relief it is recommended you continue taking this (or other joint products) for at least eight weeks.  Then, 3-6 months later, repeat this process to help rebuild any cartilage, tendons, or ligaments that may have degenerated.

Main Ingredients in NutriJoint

Glucosamine is a naturally occuring compound.  It is necessary for the body's natural production of joint lubricants necessary to maintain healthy cartilage and joint function side effects free.  Numerous published studies document glucosamine's ability to function as a chondroprotective agent.  Glucosamine provides the raw material needed for chondrocytes to regenerate cartilage.  A glucosamine deficiency caused by aging and/or trauma can lead to joint pain.  The oral consumption of glucosamine salts (among other nutrients below) provides the raw material needed for joint cartilage.  In nine European studies, the oral administration of glucosamine produced major reductions in joint pain, joint tenderness and joint swelling.  Improvements in joint function and overall physical performance were noted in these studies compared to placebo and/or the drug ibuprofen.  While ibuprofen worked faster than glucosamine in relieving pain, glucosamine was instrumental in rebuilding the joint cartilage matrix.  Even though studies show that glucosamine takes 4-10 weeks to produce noticeable results, the new formula discussed in this article has been producing noticeable reductions in inflammation and pain in most people in as little as two weeks side effects free.

Chondroitin helps to prevent destructive enzymes from attacking critical joint components.  The chondroitin sulfates provide the structural components of cartilage found in joints.  The chondroitin sulfates have been tested extensively in humans with outstanding success as heart/circulatory agent.  Research studies have provided much useful data on the safety and effectiveness of chrondroitin sulfates.  When intramuscular injections of chondroitin sulfates were given to patients, there were major reductions in joint pain and increases in joint function side effects free.  Chondroitin sulfates inhibit free radicals that degrade joint cartilage and collagen.  Chondroitin sulfates also improve blood circulation to joints, which enables antioxidants and glucosamine to enter inflamed joints to stimulate the required repair process.  Like glucosamine, chondroitin sulfate attracts water into the cartilage matrix.  Likewise, it has the ability to prevent enzymes from dissolving cartilage.  Recent studies have shown very good results from long-term treatment with chondroitin sulfate at reducing pain and increasing range of motion.  Glucosamine alone or in combination with chondroitin sulfate and MSM helps with joint pain and repair according to one of the leading authors on the subject.

MSM (methylsulphonymethane) is a naturally occurring organic sulfur compound that the body needs for healthy cell repair.  MSM promotes new cell growth and helps with allergies and parasites and side effects associated with them.  It is a high quality, bioavailable source of methyl sulfonyl methane, an organic source of sulfur shown in clinical studies to have a beneficial effect on painful conditions.  MSM has also been shown to improve blood circulation, relieve constipation and enhance the immune system.

BioCell Collagen II is a natural hydrolyzed Type 2 collagen ingredient that provides a complex matrix of elements (collagen Type 2, chondroitin sulfate and hyaluronic acid) that support joint and skin health.  With the patented process, BioCell Collagen II was developed as a low molecular weight ingredient that could be easily absorbed by the body.

The nutrients below are not included in Nutri-Joint

Vitamin C has been researched extensively concerning connective tissue strength (tendons, ligaments, arterial, and vein strength).  Vitamin C is crucial for the proper function of the enzyme proto-collagen hydroxylase, which produces collagen, the primary constituent of the granulation tissue that heals a wound and the key component in blood vessel walls.  Vitamin C must be replenished daily because it is water-soluble and any excess is excreted rather than stored thus helping to eliminate the possibilities of side effects.  The scientific literature is replete with information showing Vitamin C to be therapeutic in amounts of at least 3 grams per day (divided doses throughout the day are best).  Less than 3 grams per day consumption does not show significant benefits -- considered by most authorities on the subject.

Another supplement is SAM-e.  A two-year study involving 108 patients (97 by the end of the study) was published in the American Journal of Medicine in 1987 showing SAM-e alleviates pain and alleviates foul moods in people with joint pain.  Participants in the study were given 600 mg of SAM-e per day the first two weeks, and 400 mg/day thereafter.

Omega 3 Fatty Acids
There is now solid evidence of the value of treating joints with omega-6 essential fatty acids and omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).  These essential fatty acids are precursors of prostaglandins such as PG1, which have known positive side effects, and decrease the activity of pro-inflammatory prostaglandins such as PG2.  Here are findings from some of the new studies documenting the benefits of essential fatty acids in dealing with joints:

In the Annuals of Internal Medicine (1993 119/9), the findings of a 24-week, double-blind, placebo-controlled trial with gamma linolenic acid GLA derived from borage oil have been reported.  The patients receiving the borage oil experienced a 36% reduction in the number of tender joints, a 45% reduction in the tender joint score, a 41% reduction in the swollen joint score, and a 28% reduction in the swollen joint count.  The placebo group showed no benefits.

A paper in The British Journal of Rh (1994 33/9) reports the findings of a 24-week double-blind, placebo-controlled trial in patients with joint pain using black currant seed oil rich in gamma linolenic acid (GLA) and alpha linolenic acid.  Patients receiving black currant seed oil showed reductions in signs and symptoms.  The placebo group showed no change in their status.  The researchers concluded that their study showed that black currant seed oil is a potentially effective treatment for joints.  No adverse reactions were observed, although some people dropped out of the trial because of size and number of capsules they were required to take.

In Seminars in Arth and Rh (1995 25/2), there was a review of all the published literature on the use of gamma linolenic acid (GLA) for the treatment of joint pain.  GLA was shown to reduce the effects of joint pain on joint linings, though more research was said to be needed to determine the ideal dose of GLA for arthritis.

A study in the Journal of Clinical Epidemiology (1995 48/11) reviewed all the published studies on the use of fish oil to treat joints.  They revealed that, in general, after three months of use, there was a significant reduction in tender joint count and morning stiffness in patients receiving fish oils.  The placebo groups experienced no relief from pain.

In a study in Arth and Rh (1995 38/8), joint patients stopped taking non-steroidal anti-inflammatory drugs and switched to fish oil.  This placebo-controlled, double-blind study showed that the group receiving the fish oil experienced significant decreases in the number of tender joints, duration of morning stiffness, improvements in the physicians' and patients' evaluation of global activity, and the physicians' evaluation of pain.  Patients receiving fish oil exhibited improvement in clinical functions compared to patients receiving placebo.  Some patients were able to stop taking conventional drugs altogether.  These new studies confirm numerous previous reports showing broad-spectrum benefits when joint pain patients take EPA/DHA from fish oil and GLA from borage or black currant seed oil.

The nutrients above have been shown to:

  • Helps relieve inflammation, stiffness, and pain,

  • Support the regeneration of joint cartilage and joint lubricating synovial fluid,

  • Aids the suppression of auto-immune components that attack joint linings,

  • Have fewer side effects, especially those associated with non-steroidal anti-inflammatory drugs.

In addition, these natural ingredients have been shown to:

  • Reduce the risk of abnormal blood clot formation,

  • Help maintain the health of the endothelial linings of the arterial system,

  • Support healthy skin,

  • Help reduce serum triglyceride levels,

  • Assist with blood pressure in a minority of hypertensive patients.

Warnings Information:

  • For dietary supplement use only,
  • Keep out of reach of children,
  • Do not exceed recommended dosage,
  • If you have a bad reaction, discontinue use immediately,
  • When using Nutri-Joint / glucosamine, chondroitin sulfate, msm, sulphate supplements, please inform your physician,
  • If you are pregnant, lactating or have a medical condition, consult your health care professional before using this or any other nutritional supplement,
  • If allergic reaction or side effects occur, discontinue immediately.

NutriJoint Ingredients

Pricing Information: Nutri-Joint (Glucosamine, Chondroitin Sulfate, MSM)


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