Green Coffee Bean Extract Inhibits Calories
and Glucose Absorption!
- Page 2
As seen on the Dr. Oz Show
Reprinted by permission from Bill Faloon of The Life Extension Foundation - By Michael Downey
By this point, scientists had accumulated substantial evidence that both caffeinated and decaffeinated coffee and especially, green coffee bean extract significantly reduce the absorption of glucose,17,19,21 and the absorption of fats.13,16 There was also evidence of a decrease in the enzyme amylase,10 which would reduce the absorption of carbohydrates. These positive effects indicated that green coffee bean extract decreases absorption of calories and produces substantial weight loss.17
A 2011 review and meta-analysis of published and unpublished human studies involving randomized clinical trials using green coffee bean extract in doses of 180 mg to 200 mg daily concluded that there was an overall decrease in body weight. However, the scientists concluded that further rigorous research was needed to conclusively establish the weight-loss efficacy of the extract.42
Compelling Weight-Loss Results
In a crossover study, participants are cycled through different phases of treatment and placebo. In this case, subjects took a high dose of green coffee bean extract for 6 weeks, a lower dose green coffee bean extract for 6 weeks, and a placebo for 6 weeks in a randomized, double-blind manner. Between phases, there was a 2-week washout period, making the entire study 22 weeks long.
Crossover studies are considered sound because each person in the test group serves as his or her own control. This improves the chances of getting an accurate result, because it eliminates the possibility of the outcome reflecting a difference between the active and control groups. Instead, any difference in results can be attributed with much greater confidence to the different supplements taken.
To ensure the findings were more representative, the investigation enlisted both men and women.
Participants were restricted to those who were classified by their BMI as obese or pre-obese because those who have these conditions are subject to obesity's negative metabolic side effects and find weight loss difficult to achieve.
To avoid any confounding effect from drugs, subjects were excluded if they had taken any medications known to influence weight during the previous 6 months.
To further ensure that any effect on weight, body fat or BMI could be solely attributed to the extract, there were no significant changes in dietary calories or in the dietary percentages of carbohydrates, fat, and proteins at any time during the study. There were also no significant changes in exercise. The daily capsules were the only intervention, although in a non-study situation, people seeking weight reduction would ideally combine this intervention with lower calorie consumption and greater physical activity to promote maximum weight loss.
During the high-dose phase, subjects took 350 mg of extract, three times daily. The lower dose phase included 350 mg of extract, taken twice daily. The placebo phase involved a 350 mg dose three times daily of an inert capsule containing an inactive substance.
In January 2012, the Scientists Reported the Striking Results
The substantial anti-obesity impact was clearly reflected in the positive side effects findings that a remarkable 37% of participants who were assessed as having pre-obesity (25-30 BMI) at the start of the study had their condition reversed to the normal-weight range!28
A study follow-up showed that, contrasting with food-restriction diets, a surprising 87.5% of the test subjects were able to maintain their weight loss after completing the study.28 No negative side effects were observed.
Exploring the Biochemical Mechanisms
Whatever the mechanism through which green coffee bean extract delivers its beneficial effects, it has been shown to have a unique anti-obesity benefit: It substantially reduces body weight and body fat -- even without a change in exercise or calorie consumption!28
The good news is that scientists have found that green coffee bean extract can intervene in a unique way to inhibit the process behind obesity. Its compounds can reduce levels of fat11-16 and glucose14,15,17-27 in the body and can decrease the absorption of calories!10
In a recent, placebo-controlled study on humans, green coffee bean extract decreased weight by a remarkable average of over 17.6 pounds!28 And, 37% of participants reversed their pre-obesity status back to the normal-weight range!28 These results confirm that green coffee bean extract is a unique and potent intervention to alter obesity in a positive direction.
Green Coffee Bean Extract/Chlorogenic Acid
Extract w/Satiereal (Crocus
Sativus L.) |
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