Inositol (500mg - hexanicotinate, hexaniacinate) Effects, Benefits - Dose

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Inositol (500mg - hexanicotinate, hexaniacinate) effects, benefits - Dose
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Twin Lab Inositol Caps (500mg - hexanicotinate, hexaniacinate) Effects, Benefits - Dose
500 mg, 100 capsules

Found in muscles, inositol has been found to be essential for calcium and insulin metabolism.  Recent research indicates inositol is beneficial for stabilizing moods.

Antiplatelet Activity of Inositol Hexanicotinate
Platelet adhesion to endothelial cells, their aggregation and subsequent release of platelet-derived mediators are key steps in the formation of blood clots and hardening of the arteries. The effect of inositol on platelet aggregation and adenosine triphosphate (ATP) (cells' energy storage) release were simultaneously measured in whole blood obtained from 10 healthy volunteers. The platelets were activated with adenosine diphosphate (ADP), collagen, or thrombin in the presence or absence of inositol.  Inositol significantly inhibited platelet aggregation in a dose-response manner which were drug-induced.  Inositol strongly and significantly reduced drug-induced ATP release for collagen and for thrombin.  The results demonstrate that inositol effectively inhibits human platelet aggregation in vitro, suggesting its potential in reducing the risk for cardiovascular disease.  Full source: Anticanc Res 99, Vol. 19, Iss. 5A, Pgs. 3689-3693

Prevention of Colon canc by Components of Dietary Fiber (Inositol)
canc of colon is one of the leading causes of canc death in Western countries and is increasing rapidly in Japan.  Studies have suggested that as the intake of fiber-rich food increases, colon canc rates fall.

Dietary fiber comprises a group of non-starch polysaccharides such as cellulose, hemicellulose, and pectin and non-carbohydrate substances such as phytic acid (inositol).  Animal studies have consistently shown that dietary wheat bran reduced growth of colon tumors.  Human studies have demonstrated that supplemental wheat bran in the diet decreased the formation of metabolites that have been shown to act as tumor promoters in the colon.  Among the components of dietary fiber, especially wheat bran, inositol has been studied extensively for its chemopreventive properties against colon canc in animals.  Dietary inositol reduced the incidence of colonic abnormal depression points, and changing pre-cancous lesions in rats.  Oral administration of inositol was shown to inhibit colon canc in rodents during the initiation and post-initiation stages.  Inositol acts as an antioxidant, to reduce the rate of cell proliferation and to augment the immune system response by enhancing the activity of natural killer (NK) cells.  This data provides evidence for potential chemopreventive properties of inositol against colon canc.  Full source: Anticanc Res 99, Vol. 19, Iss. 5A, Pgs. 3681-3683

Supplement Facts:  Serving Size - 1 capsule.  Servings Per Container - 100.


Amount / Serving


500 mg

Other ingredients:  Gelatin, potato starch, purified water, magnesium stearate, MCT.

No-Flush Niacin contains a special form of niacin, inositol hexanicotinate, an ester compound formed from a six-to-one (6:1) molecular ratio (4:1 by weight) of niacin and inositol.  Its unique properties allow for true niacin activity without niacins characteristic flush that is unacceptable to many people.

Dosage and Use
One capsule once or twice daily is suggested, or as directed by a healthcare practitioner.  This product is best utilized when taken with meals.

High doses of inositol can cause diarrhea in some individuals.

Warnings Information:

  • For dietary supplement use only,

  • Keep out of reach of children,

  • Do not exceed recommended dosage,

  • If you have a bad reaction or side effects, discontinue use immediately,

  • When using, please inform your physician,

  • If you are pregnant, lactating or have a medical condition, consult your health care professional before using this or any other nutritional supplement,

  • If the effects of allergic reaction occurs when using inositol supplements, discontinue immediately.

More Information:  Inositol (1000mg - hexanicotinate, hexaniacinate) effects, benefits - Dose

 Order:   Inositol | No-Flush Niacin (inositol hexanicotinate)

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