L-Lysine Side Effects, Benefits - Herpes/Cold Sores Support

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L-Lysine May Help Prevent Herpes/Cold Sores Recurrence

L-Lysine is an essential amino acid needed for growth and to help maintain nitrogen balance in the body.  (Essential amino acids cannot be made in the body and must be supplied by the diet or supplements.)

Lysine appears to help the body absorb and conserve calcium. Lysine has many functions in the body because it is incorporated into many proteins, which are used by the body for a variety of purposes.

Most people, including vegans (vegetarians who also avoid dairy and eggs), consume adequate amounts of lysine.  However, vegans whose diets contain large amounts of grains and only minimal amounts of beans could become deficient in lysine.  Athletes involved in frequent vigorous exercise have increased need for essential amino acids, although most diets meet these increased needs.

The essential amino acid requirements of burn patients may exceed the amount of lysine in the diet.  Researchers in this field often suggest that people take 1000-3000 mg of lysine along with 700-1000 mg of BHT (butylated hydroxytoluene) per day for type 1 & 2 herpes (includes cold sores and shingles). 

In addition, baking soda soda water appears to be one of the biggest winners in herpes suppression/elimination due to the acid/alkaline imbalance in our bodies.

Lysine supplementation increases the absorption of calcium and may reduce its excretion.2  As a result, some researchers believe that lysine may eventually be shown to have a role in optimal health, side effects free.3

Lysine works with other essential amino acids to maintain growth, lean body mass, and the body's store of nitrogen.

1. Civitelli R, Villareal DT, Agneusdei D, et al. Dietary L-lysine and calcium metabolism in humans. Nutrition 1992;8:4004.
2. Civitelli R, Villareal DT, Agnusdei D, et al. Dietary L-lysine and calcium metabolism in humans. Nutrition 1992;8:4005.
3. Flodin NW. The metabolic roles, pharmacology, and toxicology of lysine. J Am Coll Nutr 1997;16:721 [review].

Earl Mindell, R.Ph., Ph.D. and Master Herbalist writes in his book "Supplement Bible,"  For more than a decade, lysine has been prescribed by natural healers and mainstream physicians ... (it) helps alleviate symptoms of and may help prevent herpes/cold sores recurrence ... Lysine is available in capsules and tablets, take 500 to 1000 mg. daily.

It would make sense to use the lysine both "topically", as an ointment, and "systemically" internally to effect the whole system.  (It might help to take ginkgo biloba too as ginkgo increases circulation to the nervous system.)

Natural form of the stuff?  Lysine is an essential amino acid: one of the 21 amino acids that make up natural proteins.  About half of these 21 amino acids can be made by the human body from other amino acids and cannot be synthesized by humans.  They must be derived nutritionally from protein intake.  These are the "essential amino acids.  (Incidently, corn and maize lacks lysine and if your diet is totally centered on maize you can suffer from a condition called "pellagra").  Most proteins are made up of a melange of most of the amino acids.  As of this time I am not aware of a source with a therapeutically useful lysine content.  (One of the sources I chased gave nutritional sources as "beans, dairy, eggs, fish, meat..." - that is to say, high protein foods and " ... potatoes ... " which is interesting because ... ) I've just received some feedback that, "Potatoes are the best natural source of lysine (with the skin on)." Nonetheless, I think that by and large you are stuck with supplements.

L-Lysine Dietary Supplement
620 mg, 100 easy to swallow capsules

Supplement Facts:  Serving Size - 1 capsule.  Servings / Container 100

Amount / Serving


620 mg


Other Ingredients:  Gelatin, magnesium stearate.  This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice.  Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Dose and Use:  Adults take one to three capsules per day, or as directed by a healthcare practitioner.  L-Lysine is best utilized when taken on an empty stomach with juice or water and is virtually side effects free.  Do not take with l-arginine supplements.

Warnings Information:
  • Keep L-lysine Amino-Acid Supplements / Vitamins out of reach of children,
  • Do not exceed recommended dose,
  • If you have a bad reaction or side effects, discontinue use immediately,
  • When using L-lysine Amino-Acid Supplements / Vitamins, please inform your physician,
  • If you are pregnant or breastfeeding, consult your health care professional before using nutritional supplements.

Cold Sores/Herpes/Lysine Side Effects - Pg 2 | Cold Sores/Herpes - Pg 3, FAQs, & References |
L-Lysine Liquid, Cold Stick, & Cream Info
| L-Lysine 300 Gm Powder - Dose

Pricing Information:  L-lysine Amino-Acid Supplements / Vitamins | BHT | Andrographis Paniculata


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