Resveratrol with Pterostilbene - Red Wine - Structure, Health / 100 & 250mg  Dose

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Resveratrol with Pterostilbene - Red Wine - Structure, Health - 60 Vegetarian Capsules, 100 or 250mg each by Life Extension 250mg, 60 Vegetarian Capsules by Life Extension
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Resveratrol with Pterostilbene - Red Wine - Structure, Health / 100mg & 250mg Dose

100 mg and 250 mg sizes, 60 Vegetarian capsules each

In 2003, the Life Extension Foundation introduced a purified resveratrol supplement that was later documented to favorably alter some of the changes in gene expression that cause us to age.  On January 25, 2009, CBS News 60 Minutes featured an in-depth report on the multiple benefits that reservatrol may confer in slowing and even reversing certain aspects of aging.

Findings from published scientific literature indicate that resveratrol may be the most effective plant extract for maintaining optimal health.1  Resveratrol, a constituent of red wine and possessing diverse biochemical and physiological actions, including estrogenic, anti-platelet, and anti-inflammatory properties, has long been suspected to have cardio-protective effects.

Scientists have hypothesized that resveratrol may be a key component of the famous French Paradox, whereby the French traditionally were protected against heart disease despite a diet high in butter and animal fats.  Resveratrol is a phytoalexin, a natural plant antibiotic which is produced by vitis vinifera as a response to attack by molds.

Because of the wide-spread use of pesticides in modern wine-making, including the practice of copper sulphation, the level of resveratrol in modern wines has plummeted.  Red wine contains resveratrol, but the quantity varies depending on where the grapes are grown, the time of harvest, and other factors. In fact, usually only 1-3 mg resveratrol per liter of red wine is currently found, even in the most robust red wines. After years of relentless research, a standardized resveratrol extract is now available as a dietary supplement.

This whole grape extract contains a spectrum of polyphenols that are naturally contained in red wine such as proanthocyanidins, anthocyanins, flavonoids, etc.

Based on studies that higher amounts of resveratrol may be additionally beneficial to your health, we offer a 100 mg and 250 mg product.

100 mg Dose

Supplement Facts:  Serving Size - 1 capsule.  Servings Per Container - 60.  Amount / Serving:

Resveratrol [100 mg trans-resveratrol and its glucosides from whole red grape (Vitis vinifera) and Polygonum cuspidatum (root) extract]

100 mg

Quercetin (as quercetin dihydrate)

120 mg

Trans-Pterostilbene (from pTeroPure)

0.25 mg
AKA
(250 mcg)

Other Ingredients for 100 mg above:  Vegetable cellulose (vegetable capsule), calcium carbonate, magnesium stearate, vegetable stearate.  Contains corn.  This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

250 mg Dose w/Synergistic Grape Berry Actives

Supplement Facts:  Serving Size - 1 capsule.  Servings Per Container - 60.  Amount / Serving:

Trans-resveratrol [from Japanese knotweed (root) and whole red grape (Vitis vinifera) extract] [also supplying glycosides (polydatin)]

250 mg

Red Grape (Full Spectrum French Red Wine Polyphenol Profile), Wild Blueberry (Vaccinium angustifolium), and Polygonum cuspidatum extract blend [supplying polyphenols, anthocyanins, OPCs, free resveratrol, resveratrol conjugates (epsilon-viniferin, trans and cis-polydatin), and resveratrol analogs (pterostilbene)]

85 mg

Quercetin (as quercetin dihydrate)

60 mg

Trans-Pterostilbene (as pure Pterospan and SMART pterostilbene)

.5 mg
AKA 500 mcg

Fisetin [from (Rhus succedanea L.) extract (stem)]

10 mg  

Other ingredients for 250 mg size above:  Vegetable cellulose (capsule), silica, vegetable stearate, maltodextrin.
Same material as research trials.
Pterospan (Pure Pterostilbene) and SMART are trademarks of Pharma Science Nutrients, Inc., and are used here under license.  All rights reserved worldwide.

What differentiates Life Extension's reservatrol? 
It provides 100% standardized trans-resveratrol plus a full spectrum of natural compounds from the grape that have demonstrated remarkable biological properties.  Most products currently on the market contain varying quantities of trans- and cis-resveratrol, and fail to provide enough trans-resveratrol for optimal results.  In addition, Life Extension has added pterostilbene, which researchers have found works in a synergistic fashion with resveratrol to activate ones longevity genes.

Research funded by Life Extension has shown that a combination of low-dose (20 milligrams) resveratrol plus grapeseed extract induced many of the favorable gene expression changes seen in calorie-restricted animals.  Other studies, however, have indicated that higher doses may be needed to obtain all of resveratrol's positive benefits including:

  • Improved insulin sensitivity,
  • Enhanced mitochondrial function,
  • Reduced expression of inflammatory factors,
  • Protection against the toxic effects of a high-fat diet.

Life Extension has meticulously evaluated published studies on reservatrol and pterostilbene to establish doses people might need to take to duplicate these remarkable laboratory findings.  The results of Life Extensions analysis yield a wide range of potentially effective doses of resveratrol and pterostilbene.

Resveratrol with Pterostilbene provides trans-resveratrol plus quercetin to facilitate resveratrol absorption.  The pterostilbene content of these formulas, 250 micrograms is equivalent to over 10 cups of blueberries and, 500 micrograms in the larger formula is equivalent to over 20 cups of blueberries.

Dosage and UseOne capsule daily is suggested, or as directed by a healthcare professional.  This product can be taken with or without food.

Warnings Information:  This product is not intended to treat, cure, prevent or diagnose any disease.

  • Keep Resveratrol with Pterostilbene extract out of reach of children,
  • Do not exceed recommended dose,
  • If you have a reaction or side effects, discontinue use immediately,
  • When using Resveratrol extract with Pterostilbene reservatrol please inform your physician.
  • If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.
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20 mg Dose/Info | Resveratrol - Wall Street Journal Article | References

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