Rhodiola Rosea (siberian) Side Effects, Extract, Root, Herb - Dosage

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Rhodiola Rosea (siberian) Extract - Side Effects, Root, Herb - Dosage

Rhodiola is a legendary adaptogenic tonifier that comes from the polar Arctic regions of Eastern Siberia.  Also known as Arctic Root, rhodiola was traditionally used to enhance stamina virtually free from side effects.  Full Spectrum Rhodiola Rosea combines an extract standardized to 0.8% salidrosides and 0.8% rosavin with a whole root extract, in order to provide the broadest spectrum of rhodiola constituents.

Rhodiola Rosea belongs to the plant family Crassulaceae.  The plant grows to a height of 12 to 30 inches and produces yellow flowers.  The name Rhodiola Rosea refers to the rose-like fragrance of the fresh cut root.

Rhodiola Rosea is one of the original and best-studied herbal adaptogens without side effects.  Adaptogens help the body adapt to internal and external stressors without stimulants or sedatives by supporting normal physiological functions throughout the body.  Because adaptogens help reduce feelings of stress, many people feel increased energy and stamina while supplementing and, for this reason, its best to take Rhodiola Rosea in the morning or mid-day.

For centuries, Rhodiola Rosea has been used in traditional medicine of Europe, particularly Russia and Scandinavia.  Various medicinal applications have appeared in scientific journals for more than 100 years.  Since 1960, 150+ pharmacological, phytochemical, and clinical studies have been published.  Rhodiola Rosea has been extensively studied as an adaptogen with many health-promoting effects without side effects.  Its properties remain largely ignored in the USA, however, there has been a recent upsurge in usage in the western world.  This may be due, in part, to the fact that the bulk of research has been published in the Slavic language.

Supplement Facts:  2 Tablets.  Tablets/Bottle - 30 or 60 Amount


Rhodiola rosea Root Extract (0.8% salidrosides and 0.8% rosavins) 625 mg  
Rhodiola rosea 4:1 Root Extract 30 mg  
Calcium 30 mg 3%

Rhodiola Rosea is similar to other plants such as Siberian and Panax ginseng.  Rhodiola produces favorable changes in a variety of diverse areas of physiological function including neurotransmitters, cardiovascular assistance, and the central nervous system.

Early Rhodiola extracts were standardized only with reference to the compound, salidroside.  Since the 1990s, the standard for true Rhodiola rosea extracts requires at least 0.8 percent salidroside and 0.8 percent rosavins.  Products that are only standardized for salidroside content may be adulterated with other Rhodiola species such as Tibetan or Indian Rhodiola.  According the the scientific literature, these products do not have the same beneficial effects as Rhodiola Rosea.

In addition to enhancing the positive side effects of endurance and stamina, there have been claims that rhodiola influences thoughts associated with sex, however, this author at the time of this writing, has not had the opportunity to experiment with it.

It appears that Rhodiola Rosea intake for a day or two can improve endurance exercise capacity but long term use does not appear to make much of a difference.  Practically speaking, it may make sense to take breaks from use.

Safety and Recommended Dosage:
Rhodiola is incredibly safe and virtually side effects free, with an estimated LD50 (lethal dose for 50 percent of test animals) for humans of 235 grams (not mg) for a 154 pound person.  Typical dosages used in human studies have ranged from 50 to 250 mg taken two or, occasionally, three times daily.  It is best taken 30 minutes before breakfast and lunch, with a third dose before an afternoon workout if necessary.  It is best not to take Rhodiola Rosea after dinner or in the evening, as it can be stimulating and may cause side effects of insomnia.  Those suffering from mania or bipolar disorder should not take it without medical supervision.  Rhodiola rosea may potentiate the action of stimulants.  Extremely sensitive individuals may need to reduce the dosage as low as 50 mg twice daily, and work up slowly to higher doses to avoid any possible side effects.

References for the above:
Brown, R. et al. Rhodiola rosea: a phytomedicinal overview. HerbalGram from the American Botanical Council at www.herbalgram.org, 2002, 56: 40-52.
Ramazanov, Z. Rhodiola rosea -- adaptogen for mental and physical health. 2003, Ch. 3. unpublished manuscript.
Brekhman, I. I. and Dardymov, I., New substances of plant origin which increase non-specific resistance. Ann Rev Pharmacol, 1969, 9: 419-30.
Ramazanov, op. cit. Ch. 5.
Ramazanov, op. cit. Ch. 2.
Ramazanov, op. cit. Ch. 8.

Rhodiola Extends Fruit Fly Life Span

A report published online ahead of print in the journal Rejuvenation Research revealed the finding of researchers the University of California, Irvine that supplementing the diet of fruit flies with the herb Rhodiola rosea extended life span by 10 percent.

Professor of pharmaceutical sciences, Mahtab Jafari and associates, gave adult fruit flies varying doses one of three Chinese herbs (Lu Duo Wei, Bu Zhong Yi Qi Tang and San Zhi Pian) or rhodiola mixed in yeast paste.  The flies received the herbs every other day for the duration of their lives.  A control group received an unsupplemented diet.

While the other three herbs did not affect the flies life span, rhodiola increased it by an average of 10 percent, equivalent to 3.5 days in males and 3.2 days in females.  The authors noted that correcting for a possible dietary restriction effect still did not eliminate the difference between supplemented and control flies.  Nor, does the effect of Rhodiola depend on dietary manipulation which strongly suggests that is not a mere dietary restriction mimetic.  (Editors note:  Fasting or calorie restriction has been show to extend lifespan.)

Rhodiola, an herb that grows in high altitude Arctic regions of Europe and Asia, is believed to have antioxidant properties, and has been used by many individuals to support positive moods, energy levels, and stress response.  Dr. Jafari is currently evaluating Rhodiolas' molecular mechanism by measuring its positive side effects on fruit flies energy metabolism, oxidative stress and antioxidant defenses and is initiating studies with Rhodiola in mice.

Although this study does not present clinical evidence that Rhodiola can extend human life, the finding that it does extend the lifespan of a model organism makes this herb a promising candidate for further anti-aging research.  Dr. Jafari commented, "Our results reveal that Rhodiola is worthy of continued study and we are now investigating why this herb may work to increase lifespan."

Warnings Information:

  • For dietary supplement use only,
  • Keep out of reach of children,
  • Do not exceed recommended dosage,
  • If you have a bad reaction or side effects, discontinue use immediately,
  • When using, please inform your physician,
  • If you are pregnant, lactating or have a medical condition, consult your health care professional before using this or any other nutritional supplement,
  • If the side effects of allergic reaction occurs, discontinue Rhodiola Rosea (siberian) extract supplements immediately.

Pricing Information: Rhodiola Rosea (siberian) Extract Supplements | Mitochondrial Energy Optimizer (contains Rhodiola) | Yohimbe Bark |
Alpha Male, Tribulus, & Tribex | Arginine | Avena Sativa | Choline w/B5 | D,L Phenylalanine | Lady-Vi Pleasure Cream |
  Pleasure Pill | Stamina-Rx | Super Mira Forte | L-Theanine | Vitamin C

More Information:  Siberian and Korean Panax Ginseng | Mitochondrial Energy Optimizer (contains Rhodiola Rosea)

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