Vitamin B-3 (niacin) by Life Extension - Side-Effects, Benefits, Vitamins, Deficiency - Dose
Many B vitamins are used in the body individually or in combination with enzymes to help release energy from carbohydrates, fat, and protein. Vitamin B coenzymes are crucial to the metabolic pathways that generate the energy needed by every cell in the body. Because they are codependent in their metabolic activities, a deficiency of one B vitamin can affect optimal functioning of organ systems throughout the body.
Niacin is the only B vitamin that can be synthesized in the body from the amino acid tryptophan.180-183 In its coenzyme forms, niacin is crucial to energy transfer reactions, particularly the metabolism of glucose, fat, and alcohol.184,185 Niacin's beneficial effects on blood lipids is well documented.186-201Caution: Niacin, in doses of one to three grams per day, is one of the safest and most effective substances to support healthy cholesterol levels. Niacin releases histamine and causes capillary dilation, which may cause a harmless flushing of the skin. This effect can be lessened by taking the niacin after eating or by starting with a low dose of 50 to100 mg. Then, as tolerance develops, you may begin increasing it progressively.
Recommended dosage:1 capsule per day.
Other Ingredients:gelatin, vegetable stearate. This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives. Non-GMO
Keep container tightly closed in a cool, dry and dark place.
|180. Am J Clin Nutr. 1981 Mar;34(3):423-7.||191. AmJ Cardiol. 1998 Dec 17;82(12A):35U-38U; discussion 39U-41U.|
|181. Am J Clin Nutr. 1980 Oct;33(10):2157-67.||192. Am J Cardiol. 1998 Sep 15;82(6):737-43.|
|182. J Nutr. 82:395-400.||193. Am J Cardiol. 1998 Sep 1;82(5):697-9, A9.|
|183. J Nutr. 73:172-6.||194. Am J Med. 1994 Oct;97(4):323-31.|
|184. J Am Diet Assoc. 1989 Dec;89(12):1748-52.||195. Arch Intern Med. 1994 Jul 25;154(14):1586-95.|
|185. Nutr Rev. 1975 Oct;33(10):289-97.||196. JAMA. 1994 Mar 2;271(9):672-7.|
|186. Arch Intern Med. 2002 Jul 22;162(14):1568-76.||197. Circulation. 1993 Jul;88(1):20-8.|
|187. Arterioscler Thromb Vasc Biol. 2001 Nov;21(11):1783-9.||198. J Am Geriatr Soc. 1992 Jan;40(1):12-8.|
|188. JAMA. 2000 Sep 13;284(10):1263-70.||199. Eur J Clin Pharmacol. 1991;40 Suppl 1:S49-S51.|
|189. Arch Intern Med. 2000 Apr 24;160(8):1177-84.||200. JAMA. 1990 Dec 19;264(23):3013-7.|
190. Am J Cardiol. 2000 May 1;85(9):1100-5.
|201. Metabolism. 1985 Jul;34(7):642-50.|
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