MacuGuard, Zeaxanthin Occular Support w/Lutein, Meso-zeaxanthin, & C3G (with or w/o Astaxanthin) by Life Extension

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Zeaxanthin MacuGuard Occular Support w/Lutein, Meso-zeaxanthin, & C3G (with  or w/o Astaxanthin) by Life Extension
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MacuGuard, Zeaxanthin Occular Support w/Lutein, Meso-zeaxanthin, & C3G (with or w/o Astaxanthin) by Life Extension
60 softgels

The macular region of the human retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and zeaxanthin, and another xanthophyll, meso-zeaxanthin.  The latter is formed from lutein in the retina (1).

Scientists long ago discovered that the carotenoids lutein and zeaxanthin help protect the macula and photoreceptor outer segments throughout the retina from photo-initiated oxidative damage.  New research has discovered that a third carotenoid, meso-zeaxanthin, is required by the aging macula to maintain its structural density.

Protecting Your Macular Density
By absorbing blue-light, the macular pigment protects the underlying photoreceptor cell layer from light damage.  The density of your macular pigment (composed of lutein, zeaxanthin, and meso-zeaxanthin) is essential to proper vision.  Unfortunately, this density declines naturally over time.  Patients with macular degeneration have been shown to have 30% less meso-zeaxanthin in their macula compared to healthy eyes (2).  One reason for this deficiency of meso-zeaxanthin is lack of ingested lutein.

Another explanation for the missing meso-zeaxanthin observed in macular degeneration may be the inability to adequately convert lutein to meso-zeaxanthin in the retina.  Eating lots of lutein and zeaxanthin containing vegetables can help maintain the structural integrity of the macula (3,4).  Unlike lutein and zeaxanthin, meso-zeaxanthin is not found in the diet, but is converted in the retina from ingested lutein.1  If taken as a supplement, meso-zeaxanthin is absorbed into the blood stream and effectively increases macular pigment levels (5).

Lutein, zeaxanthin, and meso-zeaxanthin help increase macular pigment and protect the inner eye as it is being bombarded by high energy wavelengths of light during vision.  This product gives you therapeutic doses of all three carotenoids to help preserve macular pigment density that is essential to healthy vision (6,7).  In addition, it provides a special ingredient that's scientifically proven to help fight tired eyes.

Tired Eyes?  Astaxanthin -- Knight in Shinning Armour
If you're one of the more than 72 million people in America who use a computer daily at work, you're probably familiar with eye fatigue (8).  Staring at a fixed distance object such as a computer screen for a long period of time can cause the muscles that focus your eyes (called the ciliary body) to tire or go into spasm.  This can result in physical symptoms such as head discomfort, sensitivity to glare, tiredness, soreness, dryness, and blurry vision.

Studies show that taking astaxanthin with other carotenoids protects against free-radical induced DNA damage, repairs UVA-irradiated cells, and inhibits inflammatory cell infiltration (9-12).  Astaxanthin also helps support vascular health within the eye and improves visual acuity (11).  Its fat-soluble nature offers protection to sensitive cells inside the eye (13).

Vision-Enhancing Benefits of Saffron
This formula also includes the optimal dose of saffron along with cyanidin-3-glucoside to support healthy vision.  People supplementing with saffron showed an improvement in vision as measured by them seeing an average of two additional lines on the Snellen eye chart commonly used by doctors to test vision.

C3G Supports Night Vision
Super Zeaxanthin Macuguard formula now includes C3G (Cyanidin-3-gluco-side), a cutting-edge berry flavonoid compound that helps to stimulate regeneration of rhodopsin.  Rhodopsin is a compound in the eyes that absorbs light in the retina.  As rhodopsin dramatically declines over time, it leads to a progressive loss of night vision.  By helping to maintain rhodopsin, C3G helps to support night vision.

With a special combination of ingredients that targets eye strain and protects visual acuity day and night, Super Zeaxanthin with Astaxanthin, Lutein, Meso-Zeaxanthin and C3G is an exciting breakthrough in eye care.


Supplement Facts:  Serving Size 1 softgel.  Servings Per Container 60.  

Amount Per Serving

MacuGuard® proprietary blend:
Phospholipids, marigold extract (flower) [providing 10 mg free lutein, 4 mg 
meso-zeaxanthin & trans-zeaxanthin], mixed carotenoids [providing 1.24 mg ╬▒-carotene]

173 mg

Saffron Extract (stigma) 20 mg

Zeaxanthin & Meso-zeaxanthin blend (micronized zeaxanthin, OptiLut Marigold and Lutein Plus with MZ Marigold Extract)

4 mg

Natural Astaxanthin from Zanthin CO2 extract of Haematococcus pluvialis algae (not included in Macuguard w/o Astaxanthin)

6 mg
C3G (Cyanidin-3-glucoside) [from European black currant (Ribes nigrum) extract (fruit)] 2.2 mg

Other ingredients: Olive oil, gelatin, glycerin, beeswax, purified water, sunflower lecithin, annatto, potato maltodextrin.   This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn, or rice, sugar, artificial sweeteners, flavors, colors, or preservatives.

OptiLut is a registered trademark of NutriScience Innovations, LLC. LuteinPlus and MZ are registered trademarks of Nutriproducts Ltd., 7 Marfleet, CB22 5LA, UK, licensed under US Patents 6,218,436 & 6,329,432. AstaREAL is a registered trademark of Fuji Chemical Industry Co., Ltd. Zanthin is a registered trademark of Valensa International, Inc., used under license. U.S. Patent 5,527,533.

Dosage and Use:  Take one softgel daily with or without food, or as recommended by a healthcare practitioner.  Super Zeaxanthin contains highly concentrated, natural extracts of bioavailable lutein, zeaxanthin, astaxanthin, and meso-zeaxanthin.  Do not take with fiber supplements.

Warnings Information:

  • Keep out of reach of children,
  • Do not exceed recommended dosage for the most benefits,
  • If you have a bad reaction, discontinue use immediately,
  • When using zeaxanthin, lutein, astaxanthin supplements, please inform your physician,
  • Do not take with fiber supplements.

Pricing Information:  MacuGuard Zeaxanthin, Lutein, Astaxanthin Supplements

Ingredients/Dose:  Bronze Ez | Phytobronz (canthaxanthin) | Astaxanthin

1. Invest Ophthalmol Vis Sci. 1993 May;34(6):2033-40.
2. For the Treatment and Prevention of Macular Degeneration: By Quantum Nutritionals Power Point Presentation.
3. Am J Clin Nutr. 2006 Nov;84(5):1107-22.
4. Ophthalmic Physiol Opt. 2006 Mar;26(2):137-47.
5. Program #405, Poster #B380 Macular Pigment and Serum Response to Dietary Supplementation with Meso-zeaxanthin. Sunday, May 04, 2003, 2:30 PM - 4:30 PM 124 carotenoid or retinoid binding proteins BI R.A. Bone 1A, J.T. Landrum 1B, C.Alvarez-Correa 1B, V.Etienne 1B, C.A. Ruiz 1A. APhysics, BChemistry, 1 Florida International Univ, Miami, FL.
6. Nutr Rev. 2005 Feb;63(2):59-64.
7. Ophthalmic Physiol Opt. 2006 Jul;26(4):362-71.
8. Report by the National Telecommunications and Information Administration of the US Department of Commerce. 2001 Sep.
9. J Photochem Photobiol B. 2007 Jul 27;88(1):1-10.
10. J Photochem Photobiol B. 2006 Dec 1;85(3):205-15.
11. Ophthalmology. 2008 Feb;115(2):324-333.e2.
12. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1679-85.
13. Biochimica et Biophysica Acta. 2001;1512: 251-8.


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