Cold Sores/Herpes/Fever Blisters - L-Lysine - Side Effects, Benefits

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Cold Sores/Fever Blisters/Herpes Support -- L-Lysine -- Side Effects, Benefits
by Dusty R. Green, M.Ed., Author/Research Scientist

In 1978, according to herpes research scientist Christopher Kagan, M.D:  Herpes DNA uses the amino acid L-arginine to replicate itself and form a virus.  Early studies using laboratory cultures demonstrated that L-arginine was necessary for herpes/fever blisters/cold sores growth.  It soon became clear that another amino acid, L-lysine, blocked the bio-availability of arginine.  By 1981, Dr. Griffith (Dr. Kagan's Colleague) demonstrated that lysine concentrations similar to those found in human blood could support the suppression of fever blisters/herpes/cold sores growth in lab cultures essentially side effects free.

In addition, Dr. Kagan stated, Several clinical studies have supported the efficacy of lysine supplementation in helping to suppress herpes/cold sores flare-ups.  In one survey, 88% of 1,543 herpes sufferers reported benefiting from lysine therapy.  More research on lysine is still needed, says Kagan, but lysine therapy has produced some positive results.

The evidence from several double-blind studies suggests that adequate doses of L-lysine can make fever blisters/herpes/cold sores flare-ups milder and less frequent.  Lysine probably works best when it is combined with dietary changes that restrict levels of another amino acid, arginine.  To do this, cut down on gelatin, chocolate, peanuts, almonds and other nuts, seeds, and to a lesser extent, wheat.

A double-blind placebo-controlled trial tested the efficacy of L-lysine in preventing recurring herpes simplex.  Twenty-seven individuals were given 1,000 mg of L-lysine 3 times a day for 6 months, while 25 subjects received placebo.  Those treated with L-lysine experienced, on average, 2.4 fewer fever blisters/herpes/cold sores flare-ups than the placebo group -- a significant result.  The L-lysine group also experienced significantly less severe flare-ups, absence of side effects and, shorter healing time.

Another placebo-controlled double-blind study on 41 subjects found that 1,250 mg of L-lysine per day helped, but 624 mg did not.  One study found no benefit, but it was very small.

Foods high in L-lysine include vegetables, beans, fish, turkey, and chicken.  When taken as a supplement, a typical daily dose is 1,000 mg.  L-lysine in supplement form has not been associated with any significant side effects.  However, high doses of L-lysine in animals have caused gallstones and elevated cholesterol levels.

Dose and Use:  Adults take one to three capsules per day, or as directed by a healthcare practitioner.  L-Lysine is best utilized when taken on an empty stomach with juice or water.  It is suggested that you do not take with l-arginine supplements.

Editors note (7-15-08):  After several anecdotal reports from customers/clients, in addition to the BHT/lysine factors, there appears to be a relationship to an "acid-state" in the body and a high incidence of fever blisters/herpes/cold sores related outbreaks.  While extrapolating the research on side effects associated with BHT/lysine, I discovered an additional factor that may relate to herpes suppression.  As I continue to do research in this arena, creating an alkaline environment in the body suggests a positive relationship to the suppression of this virus (not to mention, other disease states).  For further reading ...

Pricing Information:  L-lysine Amino-Acid Supplements / Vitamins | BHT | Andrographis Paniculata

L-Lysine Caps - Cold Sores/Herpes/Fever Blisters - Side Effects/Dose | Cold Sores/Herpes - Pg 3, FAQs & References |
L-Lysine 300 Gm Powder - Dose | L-Lysine Liquid, Cold Stick, & Cream Info


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