Tom Answers: No. Any excess lysine will simply be metabolized, used as fuel, or excreted.
Judy asks: I read in Sandy Shaw and Durk Pearson's book (Life Extension) that BHT (Butylated Hydroxytoluene) may be an anti-viral good for herpes simplex (cold sores) in combination with lysine. I have used this successfully over the years but have read elsewhere that BHT should not be used as it can be harmful. Is it a safe product to use periodically for a week or so?
Tom answers: Unless you have a compromised liver or are taking it in large daily doses chronically (more than 1 gram), it is safe enough to take and appears to have some benefits for many things. I am not taking it currently, but I did for many years.
Griffith RS, Walsh DE, and Myrmel KH. Use of L-lysine therapy in frequently recurrent herpes/cold sores simplex infection. Treatment and prophylaxis. Dermatologica 175: 183190, 1987.
McCune MA, Perry HO, Muller SA, et al. Support of recurrent herpes simplex infections with l-lysine monohydrochloride. Cutis 34: 366373, 1984.
DiGiovanna JJ and Blank H. Use of l-lysine in frequently recurrent herpes simplex infection: treatment and prophylaxis. Arch Dermatol 120: 4851, 1984.
Kritchevsky D, et al. Gallstone formation in hamsters: influence of specific amino acids. Nutr Rep Int 29: 117, 1984.
Lexzczynski DE, et al. Excess dietary lysine induces hypercholesterolemia in chickens. Experientia 38: 266267, 1982.
Wehner M, Schrader T, Finocchiaro P, Failla S, Consiglio G. A chiral sensor for l-arginine and l-lysine. Org Lett. 2000 Mar 9;2(5):605-8. [MEDLINE record in process]
Algert SJ, Stubblefield NE, Grasse BJ, Shragg GP, Connor JD. Assessment of dietary intake of lysine and arginine in patients with herpes/cold sores simplex. J Am Diet Assoc. 1987 Nov;87(11):1560-1.
Griffith RS, DeLong DC, Nelson JD. Relation of arginine-lysine antagonism to herpes simplex growth in tissue culture. Chemotherapy. 1981;27(3):209-13.
Griffith RS, Norins AL, Kagan C. A multicentered study of lysine therapy in herpes/cold sores simplex infection. Dermatologica. 1978;156(5):257-67.
Nutrition Home Page
The information and statements made throughout this web site have not been endorsed/evaluated by the Food and Drug Administration or any other governmental authority, unless otherwise specifically noted. We do not offer products or services for the benefits or purpose of diagnosis, prescription for, treatment of, or claims to prevent, mitigate or cure any viral or disease condition or be free from side effects. Please, seek the advice of a competent medical professional about anything you read on our site.RSS Feed