L-lysine / BHT FAQs - Herpes/Cold Sores Support & References
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L-Lysine / BHT
FAQs for Herpes/Cold Sores Support and ReferencesBelow are a few questions/comments concerning the use of l-lysine / BHT answered by Tom who is a Research Scientist with The Life Extension Foundation.
Mike asks a question concerning cold sores: Does the use of Arginine promote cold sores? I have read articles which suggest that Arginine is used by the herpes/cold sores virus to multiply. I would appreciate any information you may have on the subject. I would like to use the Arginine prior to workouts. Thanks!
Tom Answers: If you have had herpes (and therefore still have the virus latent within you) then you are best to stay away from l-arginine. However, BHT and l-lysine can do much to alleviate any herpes/cold sores outbreak. -- Tom
Doug asks: Is it possible to become toxic on l-lysine or to be poisoned by using it too long?
Tom Answers: No. Any excess lysine will simply be metabolized, used as fuel, or excreted.
Judy asks: I read in Sandy Shaw and Durk Pearson's book (Life Extension) that BHT (Butylated Hydroxytoluene) may be an anti-viral good for herpes simplex (cold sores) in combination with lysine. I have used this successfully over the years but have read elsewhere that BHT should not be used as it can be harmful. Is it a safe product to use periodically for a week or so?
Tom answers: Unless you have a compromised liver or are taking it in large daily doses chronically (more than 1 gram), it is safe enough to take and appears to have some benefits for many things. I am not taking it currently, but I did for many years.
References
Flodin NW. The metabolic roles, pharmacology, and toxicology of l-lysine. J Am Coll Nutr 16(1): 7—21, 1997.Griffith RS, Walsh DE, and Myrmel KH. Use of L-lysine therapy in frequently recurrent herpes/cold sores simplex infection. Treatment and prophylaxis. Dermatologica 175: 183—190, 1987.
McCune MA, Perry HO, Muller SA, et al. Support of recurrent herpes simplex infections with l-lysine monohydrochloride. Cutis 34: 366—373, 1984.
DiGiovanna JJ and Blank H. Use of l-lysine in frequently recurrent herpes simplex infection: treatment and prophylaxis. Arch Dermatol 120: 48—51, 1984.
Kritchevsky D, et al. Gallstone formation in hamsters: influence of specific amino acids. Nutr Rep Int 29: 117, 1984.
Lexzczynski DE, et al. Excess dietary lysine induces hypercholesterolemia in chickens. Experientia 38: 266—267, 1982.
Wehner M, Schrader T, Finocchiaro P, Failla S, Consiglio G. A chiral sensor for l-arginine and l-lysine. Org Lett. 2000 Mar 9;2(5):605-8. [MEDLINE record in process]
Algert SJ, Stubblefield NE, Grasse BJ, Shragg GP, Connor JD. Assessment of dietary intake of lysine and arginine in patients with herpes/cold sores simplex. J Am Diet Assoc. 1987 Nov;87(11):1560-1.
Griffith RS, DeLong DC, Nelson JD. Relation of arginine-lysine antagonism to herpes simplex growth in tissue culture. Chemotherapy. 1981;27(3):209-13.
Griffith RS, Norins AL, Kagan C. A multicentered study of lysine therapy in herpes/cold sores simplex infection. Dermatologica. 1978;156(5):257-67.
L-Lysine - Cold Sores/Herpes Support & Caps - Dose | Cold Sores/Herpes - Pg 2 |
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