L-Glutamine Powder/Capsules - Supplements, Benefits, Side Effects, Dose
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L-Glutamine -- One of the Top Health-Promoting Supplements in the World
Glutamine is the most abundant amino acid in the body, comprising more than 60% of the free amino acid pool in skeletal muscle and greater than 20% of total circulating amino acids.
There are many reasons for taking l-glutamine: Healthier intestines, stronger immune system, enhanced muscle tone, helps combat fatigue and blood sugar issues and encourages a more agile brain. For therapeutic uses, glutamine is especially recommended for people who suffer from problems such as irritable bowel syndrome, colitis, Chron's Disease, frequent NSAID users who need to protect their gastrointestinal tract, and anyone under heavy stress (including strenuous exercise) or recovering from injury or other trauma. It supports growth levels (when taken on an empty stomach before exercise or bedtime). It is also used by athletes to improve exercise endurance -- actually turns itself into a carbohydrate when the athlete becomes carbohydrate depleted.
Curbs the Desire for Alcohol and Carbohydrates
Glutamine is one of the 20 amino acids our body uses to build proteins. These proteins are the building blocks for most components of our bodies, including muscles, bones, hair, hormones and more. Glutamine plays a vital role in the proper functioning of many body systems. Due to its importance in the body, the use of glutamine supplementation is the focus of intense research.
Of the 20 amino acids in our bodies, nine are considered "essential" and the other 11 are termed "non-essential." The essential amino acids need to be obtained from our diet, as opposed to the non-essential ones, which our body can manufacture on its own. When we eat, the proteins we ingest are broken down by our digestive system into their individual amino acids. By linking amino acids back together in various combinations, our body synthesizes the proteins it needs.
Supports Surgery, Burns, Infections, & Prolonged Exercise
Glutamine is the most abundant amino acid in our bodies, comprising approximately half of the free amino acids in our muscles and blood.3 The majority of our glutamine is manufactured and stored in skeletal muscle. While our bodies synthesize most of the l-glutamine that we need, we also obtain some from the foods we eat. Practically all proteins we consume contain some amount of glutamine, usually in the order of 4% to 8% of their total amino acid composition. Given the average adult's daily protein intake, we probably obtain less than 10 grams of glutamine from our diet each day.4
Glutamine plays many roles in our body. Research has shown l-glutamine to be integral in the proper function bodily functions. It acts as a type of fuel for cells, especially for rapidly dividing cells such as enterocytes, colonocytes, lymphocytes and fibroblasts.5 During the manufacture of glutamine, a nitrogen molecule is taken from free ammonia in the body, thus it plays a role in protecting our bodies from high levels of ammonia and maintaining proper acid-base balance.4,6 When needed, our body can convert glutamine to sugar. Glutamine is also involved in the manufacture of other amino acids, including glutathione, an important intracellular antioxidant.4
The small intestine is by far the greatest user of glutamine in the body. Enterocytes (epithelial cells lining the small intestine) use glutamine as their primary fuel.4 It is felt that a lack of l-glutamine leads to a loss of epithelial cell integrity in the lining of the intestines. This, in turn, may allow toxins and infectious agents to enter the body.8 Most research studies concerning glutamine and the gastrointestinal system involve the addition of l-glutamine to TPN (total parenteral nutrition). Although glutamine has been shown to be beneficial when added to TPN solution, its role is still controversial and more studies are needed to determine its potential benefits and drawbacks.
Another Recommendation is to take 5 gm (1 heaping teaspoon of L-Glutamine powder) on an empty stomach before sleep and/or exercise (except in special cases mentioned throughout the article -- see link above).
When taking l-glutamine supplements, it is probably best to split the recommended dosage into two to four divided servings spread throughout the day.3
Pricing Information: L-Glutamine
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